Standard Operating Procedure (SOP) for Routine Maintenance of HPLC System

Standard Operating Procedure (SOP) for Calibration of Conductivity/TDS Meter

1. Purpose of Routine Maintenance of HPLC System

The purpose of this Standard Operating Procedure (SOP) is to establish guidelines for performing routine maintenance tasks on the High-Performance Liquid Chromatography (HPLC) system at [Company Name]. This procedure is essential for ensuring the system’s optimal performance and longevity.

2. Scope of Routine Maintenance of HPLC System

This SOP applies to all laboratory personnel responsible for maintaining and operating the HPLC system at [Company Name]. It covers routine maintenance tasks, including replacing pump seals, detector lamps, and tubing.

3. Definitions involved in Routine Maintenance of HPLC System

3.1 Routine Maintenance:

Scheduled tasks performed to prevent system issues and maintain HPLC system performance.

4. Responsibilities involved in Routine Maintenance of HPLC System

4.1. Laboratory Manager

4.1.1 Ensure that laboratory personnel are trained and competent in performing routine maintenance tasks.

4.1.2 Oversee compliance with this SOP.

4.2. Analysts

4.2.1 Perform routine maintenance tasks as outlined in this SOP.

4.2.2 Report any deviations or issues to the Laboratory Manager.

5. Routine Maintenance Tasks

5.1. Replacing Pump Seals

5.1.1 Define the frequency for replacing pump seals (e.g., every six months).

5.1.2 List the steps to replace pump seals, including tools and materials required.

5.2. Replacing Detector Lamps

5.2.1 Define the frequency for replacing detector lamps (e.g., annually).

5.2.2 List the steps to replace detector lamps, including tools and materials required.

5.3. Replacing Tubing

5.3.1 Define the frequency for replacing tubing (e.g., quarterly).

5.3.2 List the steps to replace tubing, including tools and materials required.

6. Routine Maintenance Record Keeping

6.1. Maintenance Log

6.1.1 Maintain a maintenance log to record all routine maintenance tasks performed on the HPLC system.

6.1.2 Include the date, task performed, and the name of the personnel who conducted the maintenance.

6.2. Documentation

6.2.1 Keep records of replacement parts, such as pump seals, detector lamps, and tubing.

6.2.2 Maintain a history of routine maintenance tasks and part replacements.

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