Great opportunity as Principal Scientist at Novartis – Apply before 20th June 2024


Website Novartis

About Novartis

Novartis is a Swiss multinational pharmaceutical company based in Basel, Switzerland. It is one of the largest pharmaceutical companies in the world, known for its focus on research and development in various therapeutic areas including oncology, cardiology, immunology, and neuroscience. Novartis produces a wide range of pharmaceuticals, including prescription drugs, generic drugs, vaccines, and over-the-counter medications. The company also has divisions dedicated to eye care and generic medicines. Novartis is recognized for its innovative drugs and contributions to healthcare globally.

Post: Principal Scientist – Toxicology


About the Role:
The Preclinical Safety (PCS) department within the Novartis Biomedical Research Translational Medicine Unit provides world-class preclinical safety profiling and assessment for optimal drug discovery, development, and commercialization, with state-of-the-art regulatory compliance. As a Preclinical Safety Profiling Expert, you will join our global PCS team to help us unleash the power of early safety screening and profiling approaches for advancing translational safety assessment and to drive drug discovery and development. You will bring your curious, innovative, and collaborative mindset to leverage a wealth of non-clinical safety-related data generated within our department and deploy state-of-the-art laboratory science and data exploration methods to accelerate the advancement of innovative medicines.

Key Responsibilities

  • Design and implement early safety screening & profiling strategies, including those associated with secondary pharmacology, genetic toxicology, and cardiovascular safety, in collaboration with internal and external partners.
  • Contribute to early ADME-Tox data unification, harmonization, curation, and augmentation to support the Predictive Safety Strategy.
  • Effectively communicate with customers, including experimental design, data quality, timeline requirements, and flowchart planning.
  • Understand and implement the agreed business strategy defined by local and global Preclinical Safety Profiling requirements, help to lead budget, ensuring appropriate coordination of projects.
  • Participate in cross-functional early safety screening & profiling collaborations with Novartis Biomedical Research partners to support the early derisking of compounds, drug targets, and therapeutic modalities.
  • Deliver clear and concise presentations for audiences with different expertise.
  • In collaboration with cross-functional partners, provide scientific and strategic input to support the early derisking of compounds, drug targets, and therapeutic modalities.
  • Ensure quality and compliance of data generation, analyses, and resultant reports.

Candidate Profile

  • PhD with 2+ years or MVSc/MS/M.Pharm with 6+ years of relevant work experience in pharmacology/toxicology.
  • Understands the basic concepts of hazard identification and risk assessment associated with drug ADME, off-target mitigation, genetic toxicology, and cardiovascular safety.
  • Familiar with early drug discovery processes.
  • Experience with data integrity and quality assurance practices.
  • Excellent communication skills and ability to translate analytical concepts for diverse audience and collaborators (English is our primary language).

Additional Information

  • Qualification: PhD with 2+ years or MVSc/MS/M.Pharm with 6+ years.
  • Location: Hyderabad.
  • Job ID: REQ-10004609.
  • End Date: 20th June 2024
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