Research Associate – Formulation

About the Job

The Formulation Scientist is tasked with developing and optimizing new and existing formulations across a range of products. Responsibilities include conducting research, designing experiments, and analyzing data to enhance product performance. The role involves hypothesis testing, creating novel formulations with various materials, and developing Liposomal formulations, Nano- and submicron particulate formulations, Polymeric-Based Formulations, among others. Collaboration with other departments is crucial to ensure all products meet required specifications.

Education Qualification

• M.Pharm / M.Sc. in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field of Engineering or Life Sciences. Exceptional candidates with relevant experience in formulation research and development are also considered.
• Experience: Industrial experience in product development and scale-up is advantageous.
• Knowledge: Familiarity with formulation principles, techniques, and the properties of materials used in pharmaceutical formulations.
• Skills: Proficiency in various formulation techniques, analytical methodologies, and the ability to distill and apply new ideas from literature.
• Problem-Solving: Ability to identify development challenges and propose solutions.
• Communication: Strong verbal and written communication skills for presenting scientific findings.
• Teamwork: Collaborative mindset for effective team work.
• Analytical Abilities: Proven track record of interpreting experimental data and troubleshooting.
• Learning: Willingness to rapidly learn and master new experimental techniques.

Areas of Relevant Experience

Experience in the following areas is beneficial, though not all are required:

• Drug Delivery Systems: Lipid-based (Liposomes, LNPs, solid-lipid nanoparticles) or polymer-based (Polymeric nanoparticles/microparticles) systems.
• Polymer Chemistry: Understanding molecular weight, degradation behavior, and synthesis.
• Proteins and Peptides: Basic handling, stability, and drug loading.
• Drug Delivery Systems: Sustained and controlled systems like implants and in situ depots.
• Microfluidics: For nanoparticle synthesis, encapsulation, and characterization.
• Purification Methods: Techniques such as ultrafiltration and TFF.
• Characterization Techniques: Particle size, zeta potential, pKa determination, and viscosity.
• Microscopy and Spectroscopy: TEM, SEM, Confocal, UV, Fluorescence, FTIR, Circular Dichroism, Raman, PXRD, DLS, DSC, MS, NMR.
• Analytical Techniques: For characterizing polymeric DDS, including UPLC/HPLC, drug release.
• Higher Order Structures: Analysis and characterization.
• Biophysical Characterization: Size, aggregates, instability mechanisms, thermal denaturation, ligand binding.
• Nucleic Acid Quantification: Techniques like RiboGreen assays and NanoDrop spectrophotometry.
• In Vitro and In Vivo Evaluation: Cell handling, culture, DDS evaluation, animal handling, and disease model development.

Qualified and interested candidates should send their CV to hr@drils.org by 10th June 2024 with “Formulation Lab” as the subject line. The selection process includes a phone interview followed by an in-person interview at Dr. Reddy’s Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad. Skype/teleconference interviews are available if necessary.

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